20 E Main Street
Chillicothe, OH 45601

Prime opportunity in the heart of historic downtown Chillicothe! This three-story commercial building sits prominently on Main Street, directly adjoining the beautifully restored Carlisle Building. With outstanding visibility and foot traffic, it's surrounded by thriving businesses and boasts eye-catching architecture. The main floor features a spacious storefront, formerly the long-time home of “Frank's Pawn Shop,” with large display windows and street-level access. A full basement offers abundant storage space. A separate entrance leads to a wide staircase accessing two second-floor one-bedroom, one-bath apartments—ideal for rental income or live/work flexibility. The third floor is a rare gem: a wide-open space with original coffered ceilings, tall windows, and stunning city views, ready for development into lofts, offices, or event space. Whether you're an investor or entrepreneur, this property blends charm, potential, and location in one of Chillicothe's most vibrant districts!